Pancreatitis as a severe complication of leptospirosis with fatal outcome: a case report

ABSTRACT Leptospirosis is a globally distributed zoonosis with a broad clinical spectrum. This disease mostly affects liver and kidney tissues. Other organs such as the pancreas, can be affected by leptospirosis-induced vasculitis. In addition, cardiac manifestations are common, and the presence of...

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Bibliographic Details
Published in:Revista do Instituto de Medicina Tropical de São Paulo
Main Authors: Pedro Eduardo Andrade de Carvalho Gomes, Sávio de Oliveira Brilhante, Rachel Bezerra Carvalho, Daniel Ribeiro de Sousa, Elizabeth De Francesco Daher
Format: Article in Journal/Newspaper
Language:English
Published: Universidade de São Paulo (USP) 2019
Subjects:
Leptospirosis
Arrhythmia
Acute pancreatitis
Acute kidney injury
Arctic medicine. Tropical medicine
RC955-962
Infectious and parasitic diseases
RC109-216
Arctic
Online Access:https://doi.org/10.1590/s1678-9946201961063
https://doaj.org/article/cbcb8364a74b4557bc3846659386fd09
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Summary:ABSTRACT Leptospirosis is a globally distributed zoonosis with a broad clinical spectrum. This disease mostly affects liver and kidney tissues. Other organs such as the pancreas, can be affected by leptospirosis-induced vasculitis. In addition, cardiac manifestations are common, and the presence of transient ECG abnormalities can be found in 70% of the patients. We report a male patient who presented with an atypical leptospirosis that progressed with severe acute pancreatitis, acute kidney injury and atrial fibrillation. Early diagnosis and adequate supportive therapy are crucial for the appropriated management of symptoms.

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