Risk factors associated with mortality in patients hospitalized for coronavirus disease 2019 in Rio de Janeiro, Brazil

• Published in: Revista da Sociedade Brasileira de Medicina Tropical
• Main Authors: Julio César Delgado Correal, Victor Edgar Fiestas Solórzano, Paula Hesselberg Damasco, Maria de Lourdes Martins, Adriana Guerreiro Soares de Oliveira, Carla Salles Campos, Marcos Fernando Fornasari, Elzinandes Leal de Azeredo, Paulo Vieira Damasco
• Format: Article in Journal/Newspaper
• Language: English
• Published: Sociedade Brasileira de Medicina Tropical (SBMT) 2021
• Subjects: COVID-19; Kaplan-Meier analysis; Mortality; Brazil; Arctic medicine. Tropical medicine; RC955-962; Arctic; Meier
• Online Access: https://doi.org/10.1590/0037-8682-0878-2020; https://doaj.org/article/cb8409ccb64c454bb0b56a8d43402b4e

Abstract INTRODUCTION: Understanding the mortality-associated risk factors of coronavirus disease 2019 will impact clinical decisions. METHODS: This retrospective longitudinal study included patients hospitalized for coronavirus disease in Rio de Janeiro, Brazil. The Kaplan-Meier method and multivariate Cox regression analysis were used. RESULTS: Sequential Organ Failure Assessment score of ≥2 (hazard ratio 4.614; 95% confidence interval =2.210-9.634; p<0.001) and neutrophil/lymphocyte ratio of >5 (hazard ratio=2.616; 95% confidence interval=1.303-5.252; p=0.007) were independently associated with mortality. CONCLUSIONS: Sequential Organ Failure Assessment score and neutrophil/lymphocyte ratio on admission can identify coronavirus disease patients at increased risk of death and guide subsequent clinical decisions.