Risk factors associated with mortality in patients hospitalized for coronavirus disease 2019 in Rio de Janeiro, Brazil

Abstract INTRODUCTION: Understanding the mortality-associated risk factors of coronavirus disease 2019 will impact clinical decisions. METHODS: This retrospective longitudinal study included patients hospitalized for coronavirus disease in Rio de Janeiro, Brazil. The Kaplan-Meier method and multivar...

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Bibliographic Details
Published in:Revista da Sociedade Brasileira de Medicina Tropical
Main Authors: Julio César Delgado Correal, Victor Edgar Fiestas Solórzano, Paula Hesselberg Damasco, Maria de Lourdes Martins, Adriana Guerreiro Soares de Oliveira, Carla Salles Campos, Marcos Fernando Fornasari, Elzinandes Leal de Azeredo, Paulo Vieira Damasco
Format: Article in Journal/Newspaper
Language:English
Published: Sociedade Brasileira de Medicina Tropical (SBMT) 2021
Subjects:
COVID-19
Kaplan-Meier analysis
Mortality
Brazil
Arctic medicine. Tropical medicine
RC955-962
Arctic
Meier
Online Access:https://doi.org/10.1590/0037-8682-0878-2020
https://doaj.org/article/cb8409ccb64c454bb0b56a8d43402b4e
Description
Summary:Abstract INTRODUCTION: Understanding the mortality-associated risk factors of coronavirus disease 2019 will impact clinical decisions. METHODS: This retrospective longitudinal study included patients hospitalized for coronavirus disease in Rio de Janeiro, Brazil. The Kaplan-Meier method and multivariate Cox regression analysis were used. RESULTS: Sequential Organ Failure Assessment score of ≥2 (hazard ratio 4.614; 95% confidence interval =2.210-9.634; p<0.001) and neutrophil/lymphocyte ratio of >5 (hazard ratio=2.616; 95% confidence interval=1.303-5.252; p=0.007) were independently associated with mortality. CONCLUSIONS: Sequential Organ Failure Assessment score and neutrophil/lymphocyte ratio on admission can identify coronavirus disease patients at increased risk of death and guide subsequent clinical decisions.

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