Fulminant hepatitis with microvesicular steatosis (a histologic comparison of cases occurring in Brazil - Labrea hepatitis - and in central Africa - Bangui hepatitis)

A similar histopathologic picture of fatal hepatitis associated with widespread acute fatty changes in hepatocytes and single-cell necrosis was seen in epidemic cases occurring in two distinct equatorial areas having high prevalences of HBV and HDV infections. The cases were previously considered to...

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Bibliographic Details
Published in:Revista da Sociedade Brasileira de Medicina Tropical
Main Authors: Zilton A. Andrade, Jean L. Lesbordes, Paul Ravisse, Raimundo Paraná, Aluízio Prata, João S. Barberino, Christian Trepo
Format: Article in Journal/Newspaper
Language:English
Spanish
Portuguese
Published: Sociedade Brasileira de Medicina Tropical (SBMT) 1992
Subjects:
Hepatite de Labrea
Hepatite de Bangui
Infecção delta
Hepatite espongiocítica
Arctic medicine. Tropical medicine
RC955-962
Arctic
Online Access:https://doi.org/10.1590/S0037-86821992000300001
https://doaj.org/article/ca46839062d24b14b5061b7ff1cdca4b
Description
Summary:A similar histopathologic picture of fatal hepatitis associated with widespread acute fatty changes in hepatocytes and single-cell necrosis was seen in epidemic cases occurring in two distinct equatorial areas having high prevalences of HBV and HDV infections. The cases were previously considered to be two different entities; Labrea hepatitis in Brazil, and Bangui hepatitis in the Central African Republic. However, the histopathologic findings suggest that they are pathogenetically and etiologically related to HBVand HDV infections, probably modified by some as yet unknown factor (s) present in equatorial forest zones.

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