Nosocomial Plasmodium falciparum infections confirmed by molecular typing in Medellín, Colombia

Abstract Three cases of nosocomial malaria are reported from patients of the Internal Medicine Ward of a tertiary University teaching hospital in Medellin, Colombia. Epidemiological research, based on entomological captures, medical records review and interviews of nursery staff about patient care p...

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Bibliographic Details
Published in:Malaria Journal
Main Authors: Blair Silvia, Restrepo Eliana, Franco Liliana, Arroyave Marta, Ochoa Jesus, González Lina, Maestre Amanda
Format: Article in Journal/Newspaper
Language:English
Published: BMC 2005
Subjects:
Arctic medicine. Tropical medicine
RC955-962
Infectious and parasitic diseases
RC109-216
Arctic
Online Access:https://doi.org/10.1186/1475-2875-4-9
https://doaj.org/article/c819a0a19d83488dad7b5c0077f418e3
Description
Summary:Abstract Three cases of nosocomial malaria are reported from patients of the Internal Medicine Ward of a tertiary University teaching hospital in Medellin, Colombia. Epidemiological research, based on entomological captures, medical records review and interviews of nursery staff about patient care practices potentially involving contact with blood, were carried out. Molecular characterization of Plasmodium falciparum was based on the amplification of MSP1, MSP2 and GLURP genes. This method enabled confirmation of the same P. falciparum genotype in all three patients as well as in a fourth one (index case). The presence of nosocomial malaria was confirmed and it was concluded that the most likely source of transmission was through multi-dose preparations of heparin applied to heparin locks.

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