Invasive Aspergillus fumigatus infection after Plasmodium falciparum malaria in an immuno-competent host: Case report and review of literature

Abstract Invasive fungal infection is rarely reported in association with malaria, even though malaria-associated inhibition of phagocyte function is a well-known condition. Invasive aspergillosis is frequently found in severely immuno-compromised patients but not in healthy individuals. Here, a cas...

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Bibliographic Details
Published in:Malaria Journal
Main Authors: Stremmel Wolfgang, Schnabel Philipp A, Eberhardt Ralf, Gotthardt Daniel, Ebinger Damaris, Eckerle Isabella, Junghanss Thomas, Eisenbach Christoph
Format: Article in Journal/Newspaper
Language:English
Published: BMC 2009
Subjects:
Arctic medicine. Tropical medicine
RC955-962
Infectious and parasitic diseases
RC109-216
Arctic
Online Access:https://doi.org/10.1186/1475-2875-8-167
https://doaj.org/article/c27b37710ec048778652bec5ad1acdf0
Description
Summary:Abstract Invasive fungal infection is rarely reported in association with malaria, even though malaria-associated inhibition of phagocyte function is a well-known condition. Invasive aspergillosis is frequently found in severely immuno-compromised patients but not in healthy individuals. Here, a case of pulmonary invasive aspergillosis in a previously healthy patient with severe P. falciparum malaria is presented, who was successfully treated with voriconazol and caspofungin. This is the first survival of malaria-associated invasive aspergillosis.

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