A small RNA that cooperatively senses two stacked metabolites in one pocket for gene control

Riboswitches contain an aptamer domain that recognizes a metabolite and an expression platform that regulates gene expression. Here the authors report the crystal structure of a preQ1-sensing riboswitch from Carnobacterium antarcticus that shows two metabolites in a single binding pocket.

Bibliographic Details
Published in:Nature Communications
Main Authors: Griffin M. Schroeder, Chapin E. Cavender, Maya E. Blau, Jermaine L. Jenkins, David H. Mathews, Joseph E. Wedekind
Format: Article in Journal/Newspaper
Language:English
Published: Nature Portfolio 2022
Subjects:
Science
Q
Antarc*
antarcticus
Online Access:https://doi.org/10.1038/s41467-021-27790-8
https://doaj.org/article/c1eaaded2e2042d0bb89dc2e7892de24
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spelling ftdoajarticles:oai:doaj.org/article:c1eaaded2e2042d0bb89dc2e7892de24 2023-05-15T14:02:48+02:00 A small RNA that cooperatively senses two stacked metabolites in one pocket for gene control Griffin M. Schroeder Chapin E. Cavender Maya E. Blau Jermaine L. Jenkins David H. Mathews Joseph E. Wedekind 2022-01-01T00:00:00Z https://doi.org/10.1038/s41467-021-27790-8 https://doaj.org/article/c1eaaded2e2042d0bb89dc2e7892de24 EN eng Nature Portfolio https://doi.org/10.1038/s41467-021-27790-8 https://doaj.org/toc/2041-1723 doi:10.1038/s41467-021-27790-8 2041-1723 https://doaj.org/article/c1eaaded2e2042d0bb89dc2e7892de24 Nature Communications, Vol 13, Iss 1, Pp 1-9 (2022) Science Q article 2022 ftdoajarticles https://doi.org/10.1038/s41467-021-27790-8 2022-12-31T11:30:44Z Riboswitches contain an aptamer domain that recognizes a metabolite and an expression platform that regulates gene expression. Here the authors report the crystal structure of a preQ1-sensing riboswitch from Carnobacterium antarcticus that shows two metabolites in a single binding pocket. Article in Journal/Newspaper Antarc* antarcticus Directory of Open Access Journals: DOAJ Articles Nature Communications 13 1
institution Open Polar
collection Directory of Open Access Journals: DOAJ Articles
op_collection_id ftdoajarticles
language English
topic Science
Q
spellingShingle Science
Q
Griffin M. Schroeder
Chapin E. Cavender
Maya E. Blau
Jermaine L. Jenkins
David H. Mathews
Joseph E. Wedekind
A small RNA that cooperatively senses two stacked metabolites in one pocket for gene control
topic_facet Science
Q
description Riboswitches contain an aptamer domain that recognizes a metabolite and an expression platform that regulates gene expression. Here the authors report the crystal structure of a preQ1-sensing riboswitch from Carnobacterium antarcticus that shows two metabolites in a single binding pocket.
format Article in Journal/Newspaper
author Griffin M. Schroeder
Chapin E. Cavender
Maya E. Blau
Jermaine L. Jenkins
David H. Mathews
Joseph E. Wedekind
author_facet Griffin M. Schroeder
Chapin E. Cavender
Maya E. Blau
Jermaine L. Jenkins
David H. Mathews
Joseph E. Wedekind
author_sort Griffin M. Schroeder
title A small RNA that cooperatively senses two stacked metabolites in one pocket for gene control
title_short A small RNA that cooperatively senses two stacked metabolites in one pocket for gene control
title_full A small RNA that cooperatively senses two stacked metabolites in one pocket for gene control
title_fullStr A small RNA that cooperatively senses two stacked metabolites in one pocket for gene control
title_full_unstemmed A small RNA that cooperatively senses two stacked metabolites in one pocket for gene control
title_sort small rna that cooperatively senses two stacked metabolites in one pocket for gene control
publisher Nature Portfolio
publishDate 2022
url https://doi.org/10.1038/s41467-021-27790-8
https://doaj.org/article/c1eaaded2e2042d0bb89dc2e7892de24
genre Antarc*
antarcticus
genre_facet Antarc*
antarcticus
op_source Nature Communications, Vol 13, Iss 1, Pp 1-9 (2022)
op_relation https://doi.org/10.1038/s41467-021-27790-8
https://doaj.org/toc/2041-1723
doi:10.1038/s41467-021-27790-8
2041-1723
https://doaj.org/article/c1eaaded2e2042d0bb89dc2e7892de24
op_doi https://doi.org/10.1038/s41467-021-27790-8
container_title Nature Communications
container_volume 13
container_issue 1
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