A small RNA that cooperatively senses two stacked metabolites in one pocket for gene control
Riboswitches contain an aptamer domain that recognizes a metabolite and an expression platform that regulates gene expression. Here the authors report the crystal structure of a preQ1-sensing riboswitch from Carnobacterium antarcticus that shows two metabolites in a single binding pocket.
Published in: | Nature Communications |
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Main Authors: | , , , , , |
Format: | Article in Journal/Newspaper |
Language: | English |
Published: |
Nature Portfolio
2022
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Subjects: | |
Online Access: | https://doi.org/10.1038/s41467-021-27790-8 https://doaj.org/article/c1eaaded2e2042d0bb89dc2e7892de24 |
Summary: | Riboswitches contain an aptamer domain that recognizes a metabolite and an expression platform that regulates gene expression. Here the authors report the crystal structure of a preQ1-sensing riboswitch from Carnobacterium antarcticus that shows two metabolites in a single binding pocket. |
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