Battling COVID-19: using old weapons for a new enemy

Abstract Coronavirus disease-19 (COVID-19) has reached pandemic proportions. Most of the drugs that are being tried for the treatment have not been evaluated in any randomized controlled trials. The purpose of this review was to summarize the in-vitro and in-vivo efficacy of these drugs on Severe Ac...

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Bibliographic Details
Published in:Tropical Diseases, Travel Medicine and Vaccines
Main Authors: Rohit Kumar, Nitin Gupta, Parul Kodan, Ankit Mittal, Manish Soneja, Naveet Wig
Format: Article in Journal/Newspaper
Language:English
Published: BMC 2020
Subjects:
SARS-CoV-2
Hydroxychloroquine
Lopinavir/ritonavir
Remdisivir
Nitazoxanide
Tocilizumab
Arctic medicine. Tropical medicine
RC955-962
Arctic
Online Access:https://doi.org/10.1186/s40794-020-00107-1
https://doaj.org/article/b8e300e34c73404cb45d14641bc4516c
Description
Summary:Abstract Coronavirus disease-19 (COVID-19) has reached pandemic proportions. Most of the drugs that are being tried for the treatment have not been evaluated in any randomized controlled trials. The purpose of this review was to summarize the in-vitro and in-vivo efficacy of these drugs on Severe Acute Respiratory Syndrome (SARS-CoV-2) and related viruses (SARS and Middle East Respiratory Syndrome) and evaluate their potential for re-purposing them in the management of COVID-19.

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