The efficacy of the interleukin 17 inhibitor ixekizumab in psoriatic arthritis: data from real clinical practice

The article describes the peculiarities of drug provision for patients with psoriatic arthritis (PsA) in the Republic of Karelia. We present a clinical case of effective treatment with interleukin 17 inhibitor ixekizumab (IXE) in a randomized clinical trial and real clinical practice in a patient wi...

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Bibliographic Details
Published in:Modern Rheumatology Journal
Main Authors: I. M. Marusenko, O. N. Sakovich
Format: Article in Journal/Newspaper
Language:Russian
Published: IMA-PRESS LLC 2021
Subjects:
R
Online Access:https://doi.org/10.14412/1996-7012-2021-3-86-90
https://doaj.org/article/b40a9ecaae8c4bb1aa763abd42e63332
Description
Summary:The article describes the peculiarities of drug provision for patients with psoriatic arthritis (PsA) in the Republic of Karelia. We present a clinical case of effective treatment with interleukin 17 inhibitor ixekizumab (IXE) in a randomized clinical trial and real clinical practice in a patient with PsA. The distinctive feature of this case is the severity of PsA course that was not controlled by standard methods of therapy. IXE treatment was characterized by a rapid clinical improvement of both articular and skin symptoms and subsequent achievement of remission, which lasted for 3 years (on the therapy). The forced interruption of the treatment led to the relapse of the disease in a short amount of time. In 2 years IXE therapy was resumed; after 6 months of continuing treatment a stable remission of PsA was achieved. The patient is still in clinical remission (on therapy).