The isolation of (6S, 9S)-cyclo(prolylvalyl) from marine actinomycete, by use of high speed countercurrent chromatography

The marine actinomycete B 1758 came from the actinomycete collection of the Alfred Wegener Institute for Polar and Marine Research in Bremerhafen, Germany. 1.079 g of raw extract was obtained by fermentation. Seven fractions were separated by column chromatography on silica gel. Fraction 4 was separ...

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Bibliographic Details
Main Authors: SINISA DJORDJEVIC, ANDRIJA SMELCEROVIC, MIRKO SCHIEBEL
Format: Article in Journal/Newspaper
Language:English
Published: Serbian Chemical Society 2002
Subjects:
(6S
Online Access:https://doaj.org/article/b1bae9ef8f00499eabcc4f9b3903211a
Description
Summary:The marine actinomycete B 1758 came from the actinomycete collection of the Alfred Wegener Institute for Polar and Marine Research in Bremerhafen, Germany. 1.079 g of raw extract was obtained by fermentation. Seven fractions were separated by column chromatography on silica gel. Fraction 4 was separated by high speed countercurrent chromatography. Fraction 4.6 yielded 5.2 mg of (6S, 9S)-cyclo(prolylvalyl).