Genetic relationships among serogroup B: serotype 4 Neisseria meningitidis strains

We compared the results obtained by serotyping of PorB epitopes using an expanded panel of monoclonal antibodies (mAb) including mAb 7 and mAb 10, with results obtained by RFLP of rRNA genes (ribotyping). The purpose of this study was to assess the correlation between phenotypic- and genotypic- meth...

Full description

Bibliographic Details
Main Authors: Ana Paula S. LEMOS, Claudio T. SACCHI, Maria V. PAIVA, Teresa I. YARA, Carmo Elias A. MELLES, Leonard W. MAYER
Format: Article in Journal/Newspaper
Language:English
Published: Universidade de São Paulo (USP) 2001
Subjects:
Neisseria meningitidis
Serogroup B
Serotype 4
Ribotyping
Strain differentiation
Arctic medicine. Tropical medicine
RC955-962
Infectious and parasitic diseases
RC109-216
Arctic
Online Access:https://doaj.org/article/ac0684d7693d495ca42883ad967474e8
Description
Summary:We compared the results obtained by serotyping of PorB epitopes using an expanded panel of monoclonal antibodies (mAb) including mAb 7 and mAb 10, with results obtained by RFLP of rRNA genes (ribotyping). The purpose of this study was to assess the correlation between phenotypic- and genotypic- methods for typing N. meningitidis. The ribotypes obtained using ClaI or EcoRV endonucleases grouped the strains in seven and two different patterns, respectively. This additional characterization of PorB epitopes improved the correlation between these two methods of typing N. meningitidis.

Similar Items