Bacteremia after Bacillus clausii administration for the treatment of acute diarrhea: A case report

Bacillus clausii is a gram-positive rod used as a probiotic to treat diarrhea and the side effects of antibiotics such as pseudomembranous colitis. We report a case of B. clausii bacteremia in a non-immunocompromised patient with active peptic ulcer disease and acute diarrhea. The probiotic was admi...

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Bibliographic Details
Published in:Biomédica
Main Authors: Juan Pablo García, Julián Andrés Hoyos, John Alexander Alzate, Edilberto Cristancho
Format: Article in Journal/Newspaper
Language:English
Spanish
Published: Instituto Nacional de Salud 2021
Subjects:
bacillus clausii
bacteremia
diarrhea
probiotics
gram-positive bacteria
Medicine
R
Arctic medicine. Tropical medicine
RC955-962
Arctic
Online Access:https://doi.org/10.7705/biomedica.5662
https://doaj.org/article/abe36c51a5d541f9af33b109c20bceb9
Description
Summary:Bacillus clausii is a gram-positive rod used as a probiotic to treat diarrhea and the side effects of antibiotics such as pseudomembranous colitis. We report a case of B. clausii bacteremia in a non-immunocompromised patient with active peptic ulcer disease and acute diarrhea. The probiotic was administered during the patient´s hospitalization due to diarrhea of infectious origin. B. clausii was identified in the bloodstream of the patient through Matrix-Assisted Laser Desorption Ionization-Time of Flight (MALDI-TOF) days after her discharge. Given the wide use of probiotics, we alert clinicians to consider this microorganism as a causative agent when signs of systemic infection, metabolic compromise, and hemodynamic instability establish after its administration and no pathogens have been identified that could explain the clinical course.

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