Calvarial tuberculosis: two cases in children

ABSTRACT Tuberculosis of the skull or calvarial tuberculosis (CTB) is rare. The literature until 2019 reported less than 60 cases of CTB in childhood. The authors describe two patients with CTB associated with other manifestations of TB, such as: spine and rib injuries, peripheral adenopathy, hepati...

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Bibliographic Details
Published in:Revista do Instituto de Medicina Tropical de São Paulo
Main Authors: Clemax Couto Sant’Anna, Pedro Luiz Ferreira Perinei, Ana Carolina Machado de Pessôa, Ekaterini Goudouris, Ana Cristina Cisne Frota
Format: Article in Journal/Newspaper
Language:English
Published: Universidade de São Paulo (USP) 2020
Subjects:
Tuberculosis
Calvarial tuberculosis
Children
Skeletal tuberculosis
Extrapulmonar tuberculosis
Arctic medicine. Tropical medicine
RC955-962
Infectious and parasitic diseases
RC109-216
Arctic
Online Access:https://doi.org/10.1590/s1678-9946202062068
https://doaj.org/article/a70d85e47c5743e69d585fcfc195f7ff
Description
Summary:ABSTRACT Tuberculosis of the skull or calvarial tuberculosis (CTB) is rare. The literature until 2019 reported less than 60 cases of CTB in childhood. The authors describe two patients with CTB associated with other manifestations of TB, such as: spine and rib injuries, peripheral adenopathy, hepatic and splenic involvement who improved with chemotherapy. The patients were a four-year-old and an eight-year-old child, whose diagnoses were confirmed by histopathological, bacteriological or molecular investigation. Both were not infected with the human immunodeficiency virus (HIV) and did not need orthopedic treatment.

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