Enzyme-linked immunosorbent assay ELISA for the detection of antibodies in the human leptospirosis Teste imunoenzimático (ELISA) para detecção de anticorpos circulantes da classe IgA na leptospirose humana

An Enzyme-linked immunosorbent assay ELISA was evaluated for the detection of IgA antibodies in the human leptospirosis. The assay proved to be sensitive and specific when compared with the ELISA-IgM, in the examinated serum samples. The results found suggest that IgA antibodies became positive late...

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Bibliographic Details
Published in:Revista do Instituto de Medicina Tropical de São Paulo
Main Authors: Marcos Vinícius da Silva, Eide Dias Camargo
Format: Article in Journal/Newspaper
Language:English
Published: Universidade de São Paulo (USP) 1992
Subjects:
Leptospirose humana
Anticorpos IgA
Teste ELISA-IgA
Arctic medicine. Tropical medicine
RC955-962
Infectious and parasitic diseases
RC109-216
Arctic
Online Access:https://doi.org/10.1590/S0036-46651992000300010
https://doaj.org/article/a2abd1c4023b43fea583b90d45e55d26
Description
Summary:An Enzyme-linked immunosorbent assay ELISA was evaluated for the detection of IgA antibodies in the human leptospirosis. The assay proved to be sensitive and specific when compared with the ELISA-IgM, in the examinated serum samples. The results found suggest that IgA antibodies became positive later in leptospirosis, and will can be an evolutive indicator in the development of the disease O teste imunoenzimático (ELISA) foi avaliado para detecção de anticorpos da classe IgA na leptospirose humana. Nas amostras de soro analisadas o teste demonstrou ser sensível e específico, quando comparado ao teste ELISA-IgM. Os resultados encontrados sugerem que os anticorpos da classe IgA aparecem tardiamente na leptospirose, e poderão ser um marcador sorológico evolutivo na progressão da doença

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