Delayed phenotypic expression of growth hormone transgenesis during early ontogeny in Atlantic salmon (Salmo salar)?
Should growth hormone (GH) transgenic Atlantic salmon escape, there may be the potential for ecological and genetic impacts on wild populations. This study compared the developmental rate and respiratory metabolism of GH transgenic and non-transgenic full sibling Atlantic salmon during early ontogen...
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ftdoajarticles:oai:doaj.org/article:a0bdd58e00e04a109fa8b044801854f7 2023-05-15T15:29:56+02:00 Delayed phenotypic expression of growth hormone transgenesis during early ontogeny in Atlantic salmon (Salmo salar)? Darek T R Moreau A Kurt Gamperl Garth L Fletcher Ian A Fleming 2014-01-01T00:00:00Z https://doi.org/10.1371/journal.pone.0095853 https://doaj.org/article/a0bdd58e00e04a109fa8b044801854f7 EN eng Public Library of Science (PLoS) http://europepmc.org/articles/PMC3998944?pdf=render https://doaj.org/toc/1932-6203 1932-6203 doi:10.1371/journal.pone.0095853 https://doaj.org/article/a0bdd58e00e04a109fa8b044801854f7 PLoS ONE, Vol 9, Iss 4, p e95853 (2014) Medicine R Science Q article 2014 ftdoajarticles https://doi.org/10.1371/journal.pone.0095853 2022-12-31T12:46:43Z Should growth hormone (GH) transgenic Atlantic salmon escape, there may be the potential for ecological and genetic impacts on wild populations. This study compared the developmental rate and respiratory metabolism of GH transgenic and non-transgenic full sibling Atlantic salmon during early ontogeny; a life history period of intense selection that may provide critical insight into the fitness consequences of escaped transgenics. Transgenesis did not affect the routine oxygen consumption of eyed embryos, newly hatched larvae or first-feeding juveniles. Moreover, the timing of early life history events was similar, with transgenic fish hatching less than one day earlier, on average, than their non-transgenic siblings. As the start of exogenous feeding neared, however, transgenic fish were somewhat developmentally behind, having more unused yolk and being slightly smaller than their non-transgenic siblings. Although such differences were found between transgenic and non-transgenic siblings, family differences were more important in explaining phenotypic variation. These findings suggest that biologically significant differences in fitness-related traits between GH transgenic and non-transgenic Atlantic salmon were less than family differences during the earliest life stages. The implications of these results are discussed in light of the ecological risk assessment of genetically modified animals. Article in Journal/Newspaper Atlantic salmon Salmo salar Directory of Open Access Journals: DOAJ Articles PLoS ONE 9 4 e95853 |
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Medicine R Science Q |
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Medicine R Science Q Darek T R Moreau A Kurt Gamperl Garth L Fletcher Ian A Fleming Delayed phenotypic expression of growth hormone transgenesis during early ontogeny in Atlantic salmon (Salmo salar)? |
topic_facet |
Medicine R Science Q |
description |
Should growth hormone (GH) transgenic Atlantic salmon escape, there may be the potential for ecological and genetic impacts on wild populations. This study compared the developmental rate and respiratory metabolism of GH transgenic and non-transgenic full sibling Atlantic salmon during early ontogeny; a life history period of intense selection that may provide critical insight into the fitness consequences of escaped transgenics. Transgenesis did not affect the routine oxygen consumption of eyed embryos, newly hatched larvae or first-feeding juveniles. Moreover, the timing of early life history events was similar, with transgenic fish hatching less than one day earlier, on average, than their non-transgenic siblings. As the start of exogenous feeding neared, however, transgenic fish were somewhat developmentally behind, having more unused yolk and being slightly smaller than their non-transgenic siblings. Although such differences were found between transgenic and non-transgenic siblings, family differences were more important in explaining phenotypic variation. These findings suggest that biologically significant differences in fitness-related traits between GH transgenic and non-transgenic Atlantic salmon were less than family differences during the earliest life stages. The implications of these results are discussed in light of the ecological risk assessment of genetically modified animals. |
format |
Article in Journal/Newspaper |
author |
Darek T R Moreau A Kurt Gamperl Garth L Fletcher Ian A Fleming |
author_facet |
Darek T R Moreau A Kurt Gamperl Garth L Fletcher Ian A Fleming |
author_sort |
Darek T R Moreau |
title |
Delayed phenotypic expression of growth hormone transgenesis during early ontogeny in Atlantic salmon (Salmo salar)? |
title_short |
Delayed phenotypic expression of growth hormone transgenesis during early ontogeny in Atlantic salmon (Salmo salar)? |
title_full |
Delayed phenotypic expression of growth hormone transgenesis during early ontogeny in Atlantic salmon (Salmo salar)? |
title_fullStr |
Delayed phenotypic expression of growth hormone transgenesis during early ontogeny in Atlantic salmon (Salmo salar)? |
title_full_unstemmed |
Delayed phenotypic expression of growth hormone transgenesis during early ontogeny in Atlantic salmon (Salmo salar)? |
title_sort |
delayed phenotypic expression of growth hormone transgenesis during early ontogeny in atlantic salmon (salmo salar)? |
publisher |
Public Library of Science (PLoS) |
publishDate |
2014 |
url |
https://doi.org/10.1371/journal.pone.0095853 https://doaj.org/article/a0bdd58e00e04a109fa8b044801854f7 |
genre |
Atlantic salmon Salmo salar |
genre_facet |
Atlantic salmon Salmo salar |
op_source |
PLoS ONE, Vol 9, Iss 4, p e95853 (2014) |
op_relation |
http://europepmc.org/articles/PMC3998944?pdf=render https://doaj.org/toc/1932-6203 1932-6203 doi:10.1371/journal.pone.0095853 https://doaj.org/article/a0bdd58e00e04a109fa8b044801854f7 |
op_doi |
https://doi.org/10.1371/journal.pone.0095853 |
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PLoS ONE |
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9 |
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4 |
container_start_page |
e95853 |
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1766360390565888000 |