Epidemiological and molecular characteristics of HIV-1 infection among female commercial sex workers, men who have sex with men and people living with AIDS in Paraguay Características epidemiológicas e moleculares da infecção por HIV-1 entre as mulheres que trabalham no comércio do sexo, entre homens que mantém relações sexuais com homens e nas pessoas convivendo com AIDS no Paraguai

• Published in: Revista da Sociedade Brasileira de Medicina Tropical
• Main Authors: Nicolas Aguayo, Victor Alberto Laguna-Torres, Margarita Villafane, Alma Barboza, Liliana Sosa, Gloria Chauca, Gladys Carrion, Beatriz Coenca, Juan Perez, Adolfo Galeano, Christian T. Bautista, Jose L. Sanchez, Jean K. Carr, Tadeusz Kochel
• Format: Article in Journal/Newspaper
• Language: English
• Published: Sociedade Brasileira de Medicina Tropical (SBMT) 2008
• Subjects: HIV/AIDS; Paraguai; Epidemiologia; Genótipos HIV; Países em desenvolvimento; Paraguay; Epidemiology; HIV genotypes; Developing countries; Arctic medicine. Tropical medicine; RC955-962; Arctic
• Online Access: https://doi.org/10.1590/S0037-86822008000300001; https://doaj.org/article/9eedcb44585e43e6900be5e6c09fa48a

An HIV seroprevalence and molecular study was conducted among 935 subjects: 723 female commercial sex workers, 92 men who have sex with men and 120 HIV-positive volunteers. The reported injection drug use rates were 0.7% in female commercial sex workers and 3% in men who have sex with men. Sexually transmitted infections were reported in 265 (37%) of the female commercial sex workers and 38 (41%) of the men who have sex with men. A total of 20 (2.8%) female commercial sex workers and 12 (13%) men who have sex with men became HIV infected during the study period. A history of sexually transmitted infection increased the risk of subsequent HIV infection twofold (adjusted odds ratio of 2.5) among the female commercial sex workers, while cocaine use had an adjusted odds ratios of 6.61 among men who have sex with men. From 130 samples, and based on heteroduplex mobility assaying for the env gene, with sequencing of part of pol and/or full genomes, subtype B was the predominant subtype identified (66%); followed by subtype F (22%) and subtype C (4%). Recombinant CRF12-BF strains were identified in 6% and CRF17_BF was identified in 2%. Um estudo de soroprevalência e de avaliação molecular do HIV foi realizado com 935 indivíduos: 723 mulheres que trabalhavam no comércio do sexo, 92 homens que mantinham relações sexuais com outros homens e com 120 voluntários HIV-positivos. O relato de uso de drogas injetáveis foi de 0,7% nas mulheres que trabalhavam no comércio do sexo e de 3% nos homens que mantinham relações sexuais com outros homens. Infecções sexualmente transmitidas foram relatadas por 265 (37%) das mulheres que trabalhavam no comércio do sexo e em 38 (41%) dos homens que mantinham relações sexuais com homens. Um total de 20 (2,8%) mulheres que trabalhavam no comércio do sexo e 12 (13%) homens que mantinham relações sexuais com homens se infectou com HIV durante o período do estudo. História prévia de infecção sexualmente transmitida aumentou em duas vezes o risco de infecção subseqüente por HIV (odds ratio ...