Pathogenicity of Highly Pathogenic Avian Influenza Virus (H5N1) in Adult Mute Swans

Adult, healthy mute swans were experimentally infected with highly pathogenic avian influenza virus A/Cygnus cygnus/Germany/R65/2006 subtype H5N1. Immunologically naive birds died, whereas animals with preexisting, naturally acquired avian influenza virus–specific antibodies became infected asymptom...

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Bibliographic Details
Published in:Emerging Infectious Diseases
Main Authors: Donata Kalthoff, Angele Breithaupt, Jens P. Teifke, Anja Globig, Timm Harder, Thomas C. Mettenleiter, Martin Beer
Format: Article in Journal/Newspaper
Language:English
Published: Centers for Disease Control and Prevention 2008
Subjects:
Mute swan
avian influenza
subtype H5N1
epidemiology
pathogenicity
preexposure immunity
Medicine
R
Infectious and parasitic diseases
RC109-216
Cygnus cygnus
Online Access:https://doi.org/10.3201/eid1408.080078
https://doaj.org/article/9ccf64e3bd12451ea4fc658e22746017
Description
Summary:Adult, healthy mute swans were experimentally infected with highly pathogenic avian influenza virus A/Cygnus cygnus/Germany/R65/2006 subtype H5N1. Immunologically naive birds died, whereas animals with preexisting, naturally acquired avian influenza virus–specific antibodies became infected asymptomatically and shed virus. Adult mute swans are highly susceptible, excrete virus, and can be clinically protected by preexposure immunity.

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