Cleft analysis of Zika virus non-structural protein 1

The non-structural protein 1 is an important molecule of the viruses in flavivirus group including to Zika virus. Recently, the NS1 of Zika virus was discovered. There is still no complete information of the molecular interaction of NS1 of Zika virus which can be the clue for explanation for its pat...

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Bibliographic Details
Published in:Asian Pacific Journal of Tropical Biomedicine
Main Authors: Somsri Wiwanitkit, Viroj Wiwanitkit
Format: Article in Journal/Newspaper
Language:English
Published: Wolters Kluwer Medknow Publications 2017
Subjects:
Online Access:https://doi.org/10.1016/j.apjtb.2017.07.007
https://doaj.org/article/9c223dec3fa049ea8838c786e9043c85
Description
Summary:The non-structural protein 1 is an important molecule of the viruses in flavivirus group including to Zika virus. Recently, the NS1 of Zika virus was discovered. There is still no complete information of the molecular interaction of NS1 of Zika virus which can be the clue for explanation for its pathogenesis and further drug search. Here the authors report the cleft analysis of NS1 of Zika virus and the result can be useful for future development of good diagnostic tool and antiviral drug finding for management of Zika virus.