Hereditary colorectal cancer screening: A 10-year longitudinal cohort study following an educational intervention

• Published in: Preventive Medicine Reports
• Main Authors: June C. Carroll, Joanne A. Permaul, Kara Semotiuk, Eric M. Yung, Sean Blaine, Elizabeth Dicks, Ellen Warner, Heidi Rothenmund, Mary Jane Esplen, Rahim Moineddin, John McLaughlin
• Format: Article in Journal/Newspaper
• Language: English
• Published: Elsevier 2020
• Subjects: Colorectal cancer; Cancer: screening; Family history; Family physician; Medicine; R; Canada; Newfoundland
• Online Access: https://doi.org/10.1016/j.pmedr.2020.101189; https://doaj.org/article/9ab297fb2c504e7ca8d7660769d20ff2

Family history (FH) of a first-degree relative with colorectal cancer (CRC) is associated with two to fourfold increased risk, yet screening uptake is suboptimal despite proven mortality reduction. We developed a FH-based CRC Risk Triage/Management tool for family physicians (FPs), and educational booklet for patients with CRC FH. This report describes physician referral and patient screening behavior 5 and 10 years post-educational intervention, and factors associated with screening.Longitudinal cohort study. FPs/patients in Ontario and Newfoundland, Canada were sent questionnaires at baseline (2005), 5 and 10 years (2015) following tool/booklet receipt. FPs were asked about CRC screening, patients about FH, screening type and timing. “Correct” screening was concordance with tool recommendations.Results reported for 29/121 (24%) FPs and 98/297 (33%) patients who completed all 3 questionnaires. Over 10 years 2/3 patients received the correct CRC screening test at appropriate timing (baseline 75%, 5-year 62%, 10-year 65%). About half reported their FP recommended CRC screening (5-year 51%, 10-year 63%). Fewer than half the patients correctly assessed their CRC risk (44%, 40%, 41%). Patients were less likely to have correct screening timing if female (RR 0.78; 95% CI 0.61, 0.99; p = 0.045). Patients were less likely to have both correct test and timing if moderate/high CRC risk (RR 0.66; 95% CI 0.47, 0.93; p = 0.017) and more likely if their physician recommended screening (RR1.69; 95% CI 1.15, 2.49; p = 0.007).Physician discussion of CRC risk and screening can positively impact patient screening behavior. Efforts are particularly needed for women and patients at moderate/high CRC risk.