Zika virus infection in a pregnant Canadian traveler with congenital fetal malformations noted by ultrasonography at 14-weeks gestation

Abstract Background Following emergence of Zika virus in the Americas, a devastating new congenital syndrome has been documented, leading to significant morbidity among Zika-infected fetuses and neonates. Case presentation A 29-year-old pregnant woman infected with Zika virus at 9-weeks gestation in...

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Bibliographic Details
Published in:Tropical Diseases, Travel Medicine and Vaccines
Main Authors: Kevin L. Schwartz, Tiffany Chan, Nanky Rai, Kellie E. Murphy, Wendy Whittle, Michael A. Drebot, Jonathan Gubbay, Andrea K. Boggild
Format: Article in Journal/Newspaper
Language:English
Published: BMC 2018
Subjects:
Arbovirus
Congenital infections
Fetal sonography
Pregnancy and travel
Zika virus
Arctic medicine. Tropical medicine
RC955-962
Arctic
Trinidad
Online Access:https://doi.org/10.1186/s40794-018-0062-8
https://doaj.org/article/99a2a9505d274509a1966adcdf57f543
Description
Summary:Abstract Background Following emergence of Zika virus in the Americas, a devastating new congenital syndrome has been documented, leading to significant morbidity among Zika-infected fetuses and neonates. Case presentation A 29-year-old pregnant woman infected with Zika virus at 9-weeks gestation in Trinidad presented with one-month of fever, headache, and myalgia with persistent viremia. Significant fetal abnormalities were identified at 14-week ultrasound, which is the earliest ultrasound to describe a severely affected fetus following Zika virus infection to our knowledge. Conclusions We discuss the implications of prolonged maternal viremia and the spectrum of congenital Zika syndrome detectable by fetal ultrasound.

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