Lipase-Catalyzed Dynamic Kinetic Resolution of Chiral Amines: Use of Palladium as the Racemization Catalyst
The simultaneous use of a biocatalyst (lipase Candida antarctica) and a transition-metal catalyst (palladium) makes the dynamic kinetic resolution of racemic phenylethylamine possible, conversion to the enantiomerically pure N-acylated form being 75–77% (ee = 99%).
| Main Authors: | , |
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| Format: | Article in Journal/Newspaper |
| Language: | German English French |
| Published: |
Swiss Chemical Society
1996
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| Subjects: | |
| Online Access: | https://doaj.org/article/98455d946cc249faa974c774fa566bd7 |
| Summary: | The simultaneous use of a biocatalyst (lipase Candida antarctica) and a transition-metal catalyst (palladium) makes the dynamic kinetic resolution of racemic phenylethylamine possible, conversion to the enantiomerically pure N-acylated form being 75–77% (ee = 99%). |
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