The authors report a case of bilateral Tinea nigra plantaris treated through a double-blind study with the topical antifungal agents Isoconazole and Terbinafine. The objective of the study was to clinically compare the efficacy of these two topical antifungal agents on days 10, 20 and 30 of the trea...

Full description

Bibliographic Details
Main Authors: André Luiz Rossetto, Rosana Cé Bella Cruz, Vidal Haddad Junior
Format: Article in Journal/Newspaper
Language:English
Published: Universidade de São Paulo (USP) 2013
Subjects:
Online Access:https://doaj.org/article/9292de34faa84ab290c834958fac3fb4
Description
Summary:The authors report a case of bilateral Tinea nigra plantaris treated through a double-blind study with the topical antifungal agents Isoconazole and Terbinafine. The objective of the study was to clinically compare the efficacy of these two topical antifungal agents on days 10, 20 and 30 of the treatment. No significant clinical differences were found, as all the plantar lesions regressed completely by the end of the treatment. Our conclusion was that in the case reported, the topical antifungal agents Isoconazole and Terbinafine demonstrated identical efficacy as a clinical cure. We also suggest the inclusion of injuries caused by arthropods of the Diplopoda Class in the differential diagnosis of Tinea nigra plantaris, due to the persistent acral hyperpigmentation. Os autores relatam um caso de Tinea nigra plantaris bilateral tratado através de um estudo duplo cego com os antifúngicos tópicos isoconazol e terbinafina. O objetivo do estudo foi comparar clinicamente a eficácia entre esses dois antifúngicos tópicos aos dias 10, 20 e 30 do tratamento, sendo que não foram observadas diferenças clínicas significativas, uma vez que todas as lesões plantares regrediram completamente no final do tratamento. Nossa conclusão foi que os antifúngicos tópicos isoconazol e terbinafina demonstraram a mesma eficácia na cura clínica do caso relatado. Adicionalmente, é sugerida a inclusão dos acidentes causados por artrópodos da Classe Diplopoda no diagnóstico diferencial com a Tinea nigra plantaris devido a hiperpigmentação acral persistente.