Ebola viral selenoproteins: a metallomics analysis

Ebola virus infection is the present public health problem. The trend of worldwide epidemic becomes the serious consideration for this infection. The Ebola virus infection has main clinical manifestation as acute febrile illness with hemorrhagic episode. The problem of hemostatic disturbance can be...

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Bibliographic Details
Published in:Asian Pacific Journal of Tropical Biomedicine
Main Authors: Somsri Wiwanitkit, Viroj Wiwanitkit
Format: Article in Journal/Newspaper
Language:English
Published: Wolters Kluwer Medknow Publications 2015
Subjects:
Online Access:https://doi.org/10.1016/S2221-1691(15)30161-1
https://doaj.org/article/8b0130f0b1754670975e7451b805998c
Description
Summary:Ebola virus infection is the present public health problem. The trend of worldwide epidemic becomes the serious consideration for this infection. The Ebola virus infection has main clinical manifestation as acute febrile illness with hemorrhagic episode. The problem of hemostatic disturbance can be seen. Focusing on the pathophysiology, selenium plays an important role in the blood clotting regulation. The study on the selenoprotein of the Ebola virus can be useful for further understanding on the pathology of the infection. Here, the authors use metallomics analysis for assessment of Ebola virus genome. According to this study, the selenoprotein portion within Ebola virus genome can be detected at position 1046-1115.