Sampling criteria for identifying human biomonitoring chemical differences in the Canadian Arctic
Human biomonitoring studies in the Canadian Arctic have measured a wide range of metals and persistent organic pollutants in Aboriginal and non-Aboriginal mothers during two time periods in the Northwest Territories and Nunavut. This analysis provides preliminary estimates on sample sizes and sampli...
| Published in: | International Journal of Circumpolar Health |
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| Main Authors: | , , |
| Format: | Article in Journal/Newspaper |
| Language: | English |
| Published: |
Taylor & Francis Group
2014
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| Subjects: | |
| Online Access: | https://doi.org/10.3402/ijch.v73.23467 https://doaj.org/article/88a07a4f6df04aa899dcfad9c7234202 |
| Summary: | Human biomonitoring studies in the Canadian Arctic have measured a wide range of metals and persistent organic pollutants in Aboriginal and non-Aboriginal mothers during two time periods in the Northwest Territories and Nunavut. This analysis provides preliminary estimates on sample sizes and sampling frequencies required to measure significant changes in maternal blood concentrations for PCB 153 and total mercury. For example, sample sizes of 35–40 mothers permit the detection of a 40% decrease in these chemical concentrations between two groups (e.g. communities or regions). Improvements in method sensitivity can be achieved by on-going sampling over multiple time periods (e.g. 4 or 5) in these regions, or increasing sample sizes. |
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