Hyperprocalcitonemia as a clinical prognosis in septic patients of private hospitals in the city of Cuenca–Ecuador

• Main Authors: Diego Enrique Ledesma Pacurucu, Hermel Medardo Espinosa, Carlos Enrique Flores Montesinos, Lizette Espinosa Martin, Zoila Katherine Torres, Karla Alexandra Aspiazu Hinostroza, Patricia Michelle Martínez Salazar
• Format: Article in Journal/Newspaper
• Language: English; Spanish
• Published: Universidad del Zulia,Facultad de Medicina,Departamento de Enfermedades Infecciosas y Tropicales 2020
• Subjects: sepsis; shock séptico; puntuaciones en la disfunción de órganos; Arctic medicine. Tropical medicine; RC955-962; Public aspects of medicine; RA1-1270; Arctic
• Online Access: https://doi.org/10.5281/zenodo.3593932; https://doaj.org/article/78b1057c1ac04dbc8220b6470000336d

Procalcitonin, an acute phase’s reactant, enables to establish sepsis-diagnosis’-patients status, bringing the possibility of associate it with its prognosis. The aim of this study was to determine the clinical prognosis of hyperprocalcitonemia in septical patients of private hospital centers in Cuenca–Ecuador. The study was cross-sectional, the sample were 207 patients. Data was analyzed with SPSS statistical program (25.0); analysis was done through descriptive statistic; association through Odds Ratio (OR), confidence interval (95%), considering statiscally significant values with p <0.05. Severe hyperprocalcitonemia prevalence was 63.29%, average age 67.25±19.07 years old; male sex prevailed 57% and half-blood ethnic group. A statistical association between severe hyperprocalcitonemia and longer hospital stay (≥15 days) was shown OR: 2.41 (CI 95% 1.11–5.19 p: 0.015); likewise, with in-hospital mortality OR: 9.37 (CI 95% 4.31–20.37 p: <0.000). Association was determined, but statistical significance with presence of comorbidities was not OR: 1.35 (CI 95% 0.69–2.64 p:0.243). Severe hyperprocalcitonemia was shown in almost 2/3 of patients, and there was an association with mortality increase and hospital stay