REACTIVITY OF ANTI-GP43 ANTIBODIES FROM PARACOCCIDIOIDES BRASILIENSIS ANTISERUM WITH EXTRACTS FROM CUTANEOUS LESIONS OF LOBO'S DISEASE: PRELIMINARY NOTE
We demonstrated through several immunochemical tests the presence of GP-43 from P. brasiliensis in extracts of cutaneous lesions from Jorge Lobo's disease. This glicoprotein is one of the immunodominant antigens in this species, and is used to identify it. The demonstration of GP-43 tissues inf...
Published in: | Revista do Instituto de Medicina Tropical de São Paulo |
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Main Authors: | , , , |
Format: | Article in Journal/Newspaper |
Language: | English |
Published: |
Universidade de São Paulo (USP)
1997
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Subjects: | |
Online Access: | https://doi.org/10.1590/S0036-46651997000100007 https://doaj.org/article/76e735ca245f4a51a6dedf9ceb0e45a8 |
Summary: | We demonstrated through several immunochemical tests the presence of GP-43 from P. brasiliensis in extracts of cutaneous lesions from Jorge Lobo's disease. This glicoprotein is one of the immunodominant antigens in this species, and is used to identify it. The demonstration of GP-43 tissues infected by the agent of Jorge Lobo's disease is an additional evidence for classifying it in the genera Paracoccidioides, species loboi Através de várias provas imunoquímicas foi demonstrada a presença da GP-43 em extratos de lesões cutâneas da doença de Jorge Lobo. A glicoproteína de 43 kDa é um dos antígenos dominantes do Paracoccidioides brasiliensis, permitindo a identificação desta espécie fúngica. A demonstração da GP-43 em tecidos infectados com o agente da doença de Jorge Lobo, constitui mais um argumento para colocá-lo no gênero Paracoccidioides, espécie loboi |
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