Resistencia a los antimicrobianos de bacterias potencialmente patógenas aisladas de niños preescolares asintomáticos

Abstract: Antimicrobial susceptibility studies of potentially pathogenic bacteria found in the upper respiratory tract of asymptomatic carriers allows us to establish epidemiological control to prevent the spread of resistant strains within the susceptible population. Susceptibility of 224 bacterial...

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Bibliographic Details
Main Authors: Perozo-Mena A, Castellano-González M, Ginestre-Pérez M, Ávila-Roo Y
Format: Article in Journal/Newspaper
Language:English
Spanish
Published: Universidad del Zulia,Facultad de Medicina,Departamento de Enfermedades Infecciosas y Tropicales 2002
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Online Access:https://doaj.org/article/7661067a5a5a4c7792917fcd09348343
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Summary:Abstract: Antimicrobial susceptibility studies of potentially pathogenic bacteria found in the upper respiratory tract of asymptomatic carriers allows us to establish epidemiological control to prevent the spread of resistant strains within the susceptible population. Susceptibility of 224 bacterial strains (100 S. aureus, 52 H. influenzae, 45 hemolytic streptococci, 24 pneumococci and 3 N. meningitidis) isolated from nasal and pharyngeal swabs and obtained from 200 asymptomatic preschool children, were found using the Baüer & Kirby method, following NCCLS guidelines. S. aureus strains showed high resistance levels to PG (97,97%) and erythromycin (26,19%), resistance to oxacillin was 3,03%, vancomycin resistance strains were not detected. H. influenzae exhibited the following resistance percentages: TE 40%, ATM 25%, CEC 21,15%, SXT 17,31%, C 11,54%, CIP 3,85%, AM 1,92% y RA 1,92%. All the strains were susceptible to AMC, IMP, SAM and AZT. 20,8% of isolated S. pneumoniae strains presented resistance to PG using OX disk (1µg) and 50% of them were sensitive to and 50% intermediately susceptible when MIC was determined. 71% of group B streptococci were intermediately susceptible to PG in the agar diffusion method, but all strains were susceptible to PG when the E-test method was applied. Anti-microbial agents such as: TE, AZT, CEC, AM, SXT, C and RA, routinely employed to treat H. influenzae infections showed significant levels of resistance. All N. meningitidis strains isolated, were sensitive to PG. It is necessary to determine PG-MIC of all S. pneumoniae, since some strains with resistance to PG using OX disk are sensitive to determination of MIC by PG. Resumen: El estudio de la susceptibilidad a los antimicrobianos de las bacterias potencialmente patógenas aisladas del tracto respiratorio superior de portadores asintomáticos, permite establecer medidas de control epidemiológico, tendentes a prevenir la propagación de cepas resistentes entre la población susceptible. Se determinó la susceptibilidad por el ...