Lagochilascariasis leading to severe involvement of ocular globes, ears and meninges Infecção humana por Lagochilascaris minor com envolvimento ocular, auditivo e das meninges

A case report of a 31 year-old woman from Paraíba State (North-Eastern Brazil) that presented severe involvement of ocular globes, ears and meninges. Diagnosis was established after enucleation of her left eye, when adult worms were seen in the midst of a granulomatous inflammatory process. Her resp...

Full description

Bibliographic Details
Published in:Revista do Instituto de Medicina Tropical de São Paulo
Main Authors: Renata T.R. Aquino, Maria E.R. Magliari, José Vital Filho, Maria A.L.G. Silva, Carlos A. da Conceição Lima, Antonio J. Rocha, Carlos J. Silva, Jonathan A. Rewin, Tatiana R. Nahas, Pedro Paulo Chieffi
Format: Article in Journal/Newspaper
Language:English
Published: Universidade de São Paulo (USP) 2008
Subjects:
Boa
Online Access:https://doi.org/10.1590/S0036-46652008000600009
https://doaj.org/article/72bc663c322048829aef567be9410b7e
Description
Summary:A case report of a 31 year-old woman from Paraíba State (North-Eastern Brazil) that presented severe involvement of ocular globes, ears and meninges. Diagnosis was established after enucleation of her left eye, when adult worms were seen in the midst of a granulomatous inflammatory process. Her response to the initial treatment with levamisole and cambendazole was good, but there was a relapse after the fifth month of treatment even with maintenance doses of both medications. She later received ivermectin and albendazol and responded well. Paciente do sexo feminino, com 31 anos, procedente da Paraíba, apresentava envolvimento severo de ambos os globos oculares, com perda da visão à esquerda, comprometimento da audição e das meninges. Após enucleação do olho esquerdo fragmento de helminto identificado como Lagochilascaris minor foi observado em processo inflamatório granulomatoso. Inicialmente a paciente foi tratada com levamisol e cambendazol, com bom resultado. Verificou-se, todavia, piora do quadro após cinco meses, com eliminação de larvas do ascarídeo em lesão presente na órbita esquerda, embora a medicação fosse mantida com administração periódica. Houve boa resposta terapêutica, com regressão do quadro, após substituição dos anti-helmínticos anteriores pela associação ivermectina e albendazol.