First occurrence of an autochthonous canine case of Leishmania (Leishmania) infantum chagasi in the municipality of Campinas, State of São Paulo, Brazil

An autochthonous case of visceral leishmaniasis is reported in a dog (Canis familiaris) as an apparently natural infection in a non-endemic area. DNA obtained from spleen and liver samples produced the expected fragment in a Leishmania-specific rDNA-based nested-PCR assay. The PCR product, a 490 bp...

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Bibliographic Details
Published in:Revista do Instituto de Medicina Tropical de São Paulo
Main Authors: Elisa San Martin Mouriz Savani, Douglas Presotto, Thais Roberto, Maria Cecília Gibrail de Oliveira Camargo, Sandra Regina Nicoletti D'auria, Débora Veiga Sacramento
Format: Article in Journal/Newspaper
Language:English
Published: Universidade de São Paulo (USP) 2011
Subjects:
Visceral leishmaniasis
PCR
Epidemiology
Dogs
São Paulo
Brazil
Arctic medicine. Tropical medicine
RC955-962
Infectious and parasitic diseases
RC109-216
Arctic
Online Access:https://doi.org/10.1590/S0036-46652011000400010
https://doaj.org/article/6e1aa03d8e88484488d0adb7673f70bf
Description
Summary:An autochthonous case of visceral leishmaniasis is reported in a dog (Canis familiaris) as an apparently natural infection in a non-endemic area. DNA obtained from spleen and liver samples produced the expected fragment in a Leishmania-specific rDNA-based nested-PCR assay. The PCR product, a 490 bp fragment, was sequenced and the nucleotide sequence was identical to that of Leishmania (Leishmania) infantum chagasi. These results are surprising since no autochthonous human or canine cases of visceral leishmaniasis have ever been reported in this municipality. This case suggests that natural transmission of this disease is occurring in this area.

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