Seropositivity for Chagas disease in blood donors from the state of Alagoas, Northeastern Brazil: an 11-year time series study

Abstract INTRODUCTION Chagas disease can be transmitted by blood transfusion. Herein, we assessed the seropositivity for Chagas disease in blood donors from Alagoas, during 2010-2020. METHODS Data were requested from the Alagoas blood center. Time trend analysis was performed using a joinpoint regre...

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Bibliographic Details
Published in:Revista da Sociedade Brasileira de Medicina Tropical
Main Authors: Sílvia Letícia da Conceição Abreu, Márcio Bezerra-Santos, Flávia Silva Damasceno
Format: Article in Journal/Newspaper
Language:English
Published: Sociedade Brasileira de Medicina Tropical (SBMT) 2021
Subjects:
Chagas disease
Blood donors
Transfusional transmission disease
Arctic medicine. Tropical medicine
RC955-962
Arctic
Online Access:https://doi.org/10.1590/0037-8682-0339-2021
https://doaj.org/article/6cf34c6813644172906bb492a8fc0092
Description
Summary:Abstract INTRODUCTION Chagas disease can be transmitted by blood transfusion. Herein, we assessed the seropositivity for Chagas disease in blood donors from Alagoas, during 2010-2020. METHODS Data were requested from the Alagoas blood center. Time trend analysis was performed using a joinpoint regression model. RESULTS Seropositivity rate during the study period was 0.35%, which decreased from 2014 to 2020, (annual percentage change, APC = -29.38; p-value <0.05), while the total number of tests performed remained stable (APC = 6.5). CONCLUSIONS Despite the drop in the seropositivity for Chagas infection in donors, it is imperative to maintain the screening of donors for the epidemiological control.

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