Seroprevalencia de anticuerpos para Citomegalovirus, Toxoplasma gondii virus de hepatitis A y B en el niño desnutrido grave
ABSTRACT: During the last two decades, a number of research studies have boarded the matter of Child Malnutrition trying to understand and explain all of the changes that have occurred as consequence of the reduction of proteic-calorical intake. Today we know of the changes occurring in the immunity...
| Main Authors: | , , , , , , , |
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| Format: | Article in Journal/Newspaper |
| Language: | English Spanish |
| Published: |
Universidad del Zulia,Facultad de Medicina,Departamento de Enfermedades Infecciosas y Tropicales
2000
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| Subjects: | |
| Online Access: | https://doaj.org/article/6c729d549bba42f2aea2b65ee883da80 |
| Summary: | ABSTRACT: During the last two decades, a number of research studies have boarded the matter of Child Malnutrition trying to understand and explain all of the changes that have occurred as consequence of the reduction of proteic-calorical intake. Today we know of the changes occurring in the immunity system and day by day more research is made on new matters in this field. Anyhow, little is known of the response of the malnourished when exposed to some infectious diseases such as those produced by Citomegalovirus (CMV), Hepatitis virus types A and B and Toxoplasma. In the object of acknowledging this aspect a serological study was performed to investigate the antibodies directed against Hepatitis virus types A and B, CMV and Toxoplasma gondii in a population of 64 gravely malnourished children between 6 and 24 months of age comparing these with a group of 35 similarly aged (eutrophic) children which made up the control group. CMV seroprevalence was 48.4% in the malnourished children group in comparison to 34,2% in the control group. Likewise, Toxoplasma gondii seroprevalence percentage was higher in the malnourished group (10.9%) than in the in the control group (2,8%). No differences were encountered in Hepatitis virus type A seroprevalence between the malnourished group and control group, whilst only one malnourished individual showed IgM positive anticore antibodies (indicators of a recent infection) and none appeared in the control group. When studying recent infection through the investigation of lgM specific antibodies it was found that for CMV, 22% of the malnourished patients had been recently infected in comparison to 8.3% of the control group. Recent toxoplasmosis infection was evidenced in 57.1% of the cases, none of these occurring within the control group. Recent Hepatitis virus type A infection was not observed in any of the two groups. The major percentage of recently infected patients for Toxoplasma gondii and CMV were in the 12 to 24-month age group. These results bring us to the conclusion that ... |
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