Hypothalamic remodeling of thyroid hormone signaling during hibernation in the arctic ground squirrel

Arctic ground squirrels hibernating in darkness activate the pars tuberalis - hypothalamus thyroid hormone signaling pathway, remodel hypothalamic tanycytes, and activate the reproductive axis.

Bibliographic Details
Published in:Communications Biology
Main Authors: Helen E. Chmura, Cassandra Duncan, Ben Saer, Jeanette T. Moore, Brian M. Barnes, C. Loren Buck, Helen C. Christian, Andrew S. I. Loudon, Cory T. Williams
Format: Article in Journal/Newspaper
Language:English
Published: Nature Portfolio 2022
Subjects:
Online Access:https://doi.org/10.1038/s42003-022-03431-8
https://doaj.org/article/6832b2903caa4c0e9e095e8e29ccf0e8
Description
Summary:Arctic ground squirrels hibernating in darkness activate the pars tuberalis - hypothalamus thyroid hormone signaling pathway, remodel hypothalamic tanycytes, and activate the reproductive axis.