Rapid phenotyping towards personalized malaria medicine

Abstract Malaria is major public health concerns which continues to claim the lives of more than 435,000 people each year. The challenges with anti-malarial drug resistance and detection of low parasitaemia forms an immediate barrier to achieve the fast-approaching United Nations Sustainable Develop...

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Bibliographic Details
Published in:Malaria Journal
Main Authors: Maria Isabel Veiga, Weng Kung Peng
Format: Article in Journal/Newspaper
Language:English
Published: BMC 2020
Subjects:
Online Access:https://doi.org/10.1186/s12936-020-3149-4
https://doaj.org/article/660df0f601a04f07862c35399693a5d4
Description
Summary:Abstract Malaria is major public health concerns which continues to claim the lives of more than 435,000 people each year. The challenges with anti-malarial drug resistance and detection of low parasitaemia forms an immediate barrier to achieve the fast-approaching United Nations Sustainable Development Goals of ending malaria epidemics by 2030. In this Opinion article, focusing on the recent published technologies, in particularly the nuclear magnetic resonance (NMR)-based diagnostic technologies, the authors offer their perspectives and highlight ways to bring these point-of-care technologies towards personalized medicine. To this end, they advocate an open sourcing initiative to rapidly close the gap between technological innovations and field implementation.