Leishmaniases: Still alarming at 2018 in Bangladesh

All over the world approximately 98 countries faces endemic outbreak of leishmaniases, which is a group of parasitic disease. More than 350 million people reside under the risk of these diseases and new cases per year is about 0.7 to 1.3 million. The culprit and contagious agent Leishmania donovani...

Full description

Bibliographic Details
Published in:Asian Pacific Journal of Tropical Medicine
Main Authors: Md Misbahul Ferdous, Effat Un Nesa, Atm Rezaul Karim
Format: Article in Journal/Newspaper
Language:English
Published: Wolters Kluwer Medknow Publications 2018
Subjects:
Online Access:https://doi.org/10.4103/1995-7645.243090
https://doaj.org/article/6334ced230c348dca8b9d34a1b972cce
Description
Summary:All over the world approximately 98 countries faces endemic outbreak of leishmaniases, which is a group of parasitic disease. More than 350 million people reside under the risk of these diseases and new cases per year is about 0.7 to 1.3 million. The culprit and contagious agent Leishmania donovani (L. donovani), which is responsible for leishmaniases are breed mainly in South Asian constituency that harbor’s mainly the visceral leishmaniases (VL) globally. The inter-relationship within main etiological factor (L. donovani & remaining species of leishmaniases) and resultant biological events has been confronted in past years. For this reason there have been accentuated condition of reconsidering the formerly categorization. Rendering to the latest WHO data published in 2017 about leishmaniases death in bangladesh grasped to 988 or 0.13% of total mortality. The age of mortality rate is 0.61 per 100 000 of population, that ranks 7th in whole over the world. This disease can present mainly by three forms: cutaneous, mucocutaneous, and VL. Skin ulcer is the main presentation of cutaneous form, where in the mucocutaneous types, it present with skin ulcer with pyrexia, reduced RBC, hepatomegaly and splenomegaly. Whereas, VL well known as Kala-a-zar, which is focal, huddled inside the households, as well as typically cope the poor people. Also, VL stretches the poverty episode; nevertheless, loss of throughput and highly expensive treatment policy for affected families. Etiological factors for infectivity including residing area within 50 m fom the infected area or home as well as malnutrition and household ailments including splintered mud wall. Though the vector control is essential requirement for disease abolition, but there has been a noticeable lack of innovations from many years back. In addition, there have been many sorts of remarkable improvement in the field of diagnosis of disease as well as therapeutic intervention and vaccination protocol development. But also many kinds of obstacles arise. For ...