The radioprotective effect of a wheat germ diet on rat myocardial tissue exposed to X-rays
Abstract Introduction: To determine whether a diet of wheat (Triticum aestivum) germ has a radioprotective effect on albino rat (Rattus rattus var. Albinus) myocardial tissue. Method: Rats between 200 and 250 g were divided into 4 groups of 6 each: Two groups were fed either a wheat diet or regular...
| Published in: | Ars Pharmaceutica (Internet) |
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| Main Authors: | , , , |
| Format: | Article in Journal/Newspaper |
| Language: | English Spanish |
| Published: |
Facultad de Farmacia, Universidad de Granada
2020
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| Subjects: | |
| Online Access: | https://doi.org/10.30827/ars.v60i4.10226 https://doaj.org/article/62dd752b35144e9d95946a1434b706ee |
| Summary: | Abstract Introduction: To determine whether a diet of wheat (Triticum aestivum) germ has a radioprotective effect on albino rat (Rattus rattus var. Albinus) myocardial tissue. Method: Rats between 200 and 250 g were divided into 4 groups of 6 each: Two groups were fed either a wheat diet or regular diet 16 days before and after a single exposure to 18 mSv of X-rays. The other two groups were fed the same diets but not exposed to X-rays. The animals were sacrificed, and heart tissue was submitted to histopathological study. Results: Rats fed a standard diet and exposed to X-rays presented marked hyperemia of blood vessels, necrosis, presence of connective tissue fibrocytes, loss of muscle architecture and radial arrangement. Exposed rats fed a wheat diet presented with only light necrosis and the presence of fibrocytes. Rats not exposed to X-rays had healthy myocardia. Conclusions: Wheat germ diet may have a radioprotective effect on rat myocardium. |
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