Infection and immune-mediated meningococcal-associated arthritis: combination features in the same patient

We present a case of a 16-year-old male patient with sudden-onset, rash, arthritis and meningitis by Neisseria meningitidis one week after an acute upper respiratory infection. On the 10th day of treatment followed by neurological and arthritis clinical improvement, he presented once again a tender...

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Bibliographic Details
Published in:Revista do Instituto de Medicina Tropical de São Paulo
Main Authors: Karim Yaqub Ibrahim, Noemia Barbosa Carvalho, Maria Luisa do Nascimento Moura, Felipe Maia de Toledo Piza, Evanthia Vetos Mimicos, Yeh-Li Ho, Francisco Oscar de Siqueira França
Format: Article in Journal/Newspaper
Language:English
Published: Universidade de São Paulo (USP) 2012
Subjects:
Meningococcal disease
Arthritis
Neisseria meningitides
Arctic medicine. Tropical medicine
RC955-962
Infectious and parasitic diseases
RC109-216
Arctic
Online Access:https://doi.org/10.1590/S0036-46652012000200009
https://doaj.org/article/60ec0a3cec564424895ee903d72ad155
Description
Summary:We present a case of a 16-year-old male patient with sudden-onset, rash, arthritis and meningitis by Neisseria meningitidis one week after an acute upper respiratory infection. On the 10th day of treatment followed by neurological and arthritis clinical improvement, he presented once again a tender and swollen left knee with a moderate effusion, and active and passive range of motion was severely limited secondary to pain, and when he was submitted to surgical drainage and synovial fluid analysis he showed inflammatory characteristics. A non-steroidal anti-inflammatory drug was taken for five days with complete improvement of symptoms. The case is notable for its combination of features of septic and immune-mediated arthritis, which has rarely been reported in the same patient.

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