Enhancement of glucose uptake in muscular cell by peptide fractions separated by electrodialysis with filtration membrane from salmon frame protein hydrolysate
Consumption of fish has been positively associated with a lower risk of type 2 diabetes. In this study, the influence of pH on the separation of bioactive peptides with antidiabetic effects from Atlantic salmon frame protein hydrolysates by electrodialysis with filtration membranes (EDFM) was invest...
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ftdoajarticles:oai:doaj.org/article:6065019848174b329066a76fc0423e03 2023-05-15T15:32:24+02:00 Enhancement of glucose uptake in muscular cell by peptide fractions separated by electrodialysis with filtration membrane from salmon frame protein hydrolysate Cyril Roblet Muhammad Javeed Akhtar Sergey Mikhaylin Geneviève Pilon Tom Gill André Marette Laurent Bazinet 2016-04-01T00:00:00Z https://doi.org/10.1016/j.jff.2016.01.003 https://doaj.org/article/6065019848174b329066a76fc0423e03 EN eng Elsevier http://www.sciencedirect.com/science/article/pii/S1756464616000049 https://doaj.org/toc/1756-4646 1756-4646 doi:10.1016/j.jff.2016.01.003 https://doaj.org/article/6065019848174b329066a76fc0423e03 Journal of Functional Foods, Vol 22, Iss , Pp 337-346 (2016) Bioactive peptide fractions Cationic peptides Anionic peptides Salmon protein hydrolysate Glucose uptake Electrodialysis with filtration membrane Nutrition. Foods and food supply TX341-641 article 2016 ftdoajarticles https://doi.org/10.1016/j.jff.2016.01.003 2022-12-31T06:52:46Z Consumption of fish has been positively associated with a lower risk of type 2 diabetes. In this study, the influence of pH on the separation of bioactive peptides with antidiabetic effects from Atlantic salmon frame protein hydrolysates by electrodialysis with filtration membranes (EDFM) was investigated. The results demonstrated that pH had no significant effect on final peptide concentration in either anionic (APC) or cationic peptide compartments (CPC) during EDFM but allowed the concentration of specific peptides that contained high concentrations of Glu, Ala, Lys, Arg and His residues. Moreover, the final feed compartment (FFC) and CPC after EDFM treatment at pH 6 were able to significantly enhance glucose uptake in L6 skeletal muscle cells grown in culture. The maximum enhancement of glucose uptake (40%) was demonstrated in cells treated with the FFC fraction at 1 ng/mL without insulin while a synergetic effect of FFC peptides at 1 ng/mL with insulin was observed (enhancement of glucose uptake by 31%). Article in Journal/Newspaper Atlantic salmon Directory of Open Access Journals: DOAJ Articles Journal of Functional Foods 22 337 346 |
institution |
Open Polar |
collection |
Directory of Open Access Journals: DOAJ Articles |
op_collection_id |
ftdoajarticles |
language |
English |
topic |
Bioactive peptide fractions Cationic peptides Anionic peptides Salmon protein hydrolysate Glucose uptake Electrodialysis with filtration membrane Nutrition. Foods and food supply TX341-641 |
spellingShingle |
Bioactive peptide fractions Cationic peptides Anionic peptides Salmon protein hydrolysate Glucose uptake Electrodialysis with filtration membrane Nutrition. Foods and food supply TX341-641 Cyril Roblet Muhammad Javeed Akhtar Sergey Mikhaylin Geneviève Pilon Tom Gill André Marette Laurent Bazinet Enhancement of glucose uptake in muscular cell by peptide fractions separated by electrodialysis with filtration membrane from salmon frame protein hydrolysate |
topic_facet |
Bioactive peptide fractions Cationic peptides Anionic peptides Salmon protein hydrolysate Glucose uptake Electrodialysis with filtration membrane Nutrition. Foods and food supply TX341-641 |
description |
Consumption of fish has been positively associated with a lower risk of type 2 diabetes. In this study, the influence of pH on the separation of bioactive peptides with antidiabetic effects from Atlantic salmon frame protein hydrolysates by electrodialysis with filtration membranes (EDFM) was investigated. The results demonstrated that pH had no significant effect on final peptide concentration in either anionic (APC) or cationic peptide compartments (CPC) during EDFM but allowed the concentration of specific peptides that contained high concentrations of Glu, Ala, Lys, Arg and His residues. Moreover, the final feed compartment (FFC) and CPC after EDFM treatment at pH 6 were able to significantly enhance glucose uptake in L6 skeletal muscle cells grown in culture. The maximum enhancement of glucose uptake (40%) was demonstrated in cells treated with the FFC fraction at 1 ng/mL without insulin while a synergetic effect of FFC peptides at 1 ng/mL with insulin was observed (enhancement of glucose uptake by 31%). |
format |
Article in Journal/Newspaper |
author |
Cyril Roblet Muhammad Javeed Akhtar Sergey Mikhaylin Geneviève Pilon Tom Gill André Marette Laurent Bazinet |
author_facet |
Cyril Roblet Muhammad Javeed Akhtar Sergey Mikhaylin Geneviève Pilon Tom Gill André Marette Laurent Bazinet |
author_sort |
Cyril Roblet |
title |
Enhancement of glucose uptake in muscular cell by peptide fractions separated by electrodialysis with filtration membrane from salmon frame protein hydrolysate |
title_short |
Enhancement of glucose uptake in muscular cell by peptide fractions separated by electrodialysis with filtration membrane from salmon frame protein hydrolysate |
title_full |
Enhancement of glucose uptake in muscular cell by peptide fractions separated by electrodialysis with filtration membrane from salmon frame protein hydrolysate |
title_fullStr |
Enhancement of glucose uptake in muscular cell by peptide fractions separated by electrodialysis with filtration membrane from salmon frame protein hydrolysate |
title_full_unstemmed |
Enhancement of glucose uptake in muscular cell by peptide fractions separated by electrodialysis with filtration membrane from salmon frame protein hydrolysate |
title_sort |
enhancement of glucose uptake in muscular cell by peptide fractions separated by electrodialysis with filtration membrane from salmon frame protein hydrolysate |
publisher |
Elsevier |
publishDate |
2016 |
url |
https://doi.org/10.1016/j.jff.2016.01.003 https://doaj.org/article/6065019848174b329066a76fc0423e03 |
genre |
Atlantic salmon |
genre_facet |
Atlantic salmon |
op_source |
Journal of Functional Foods, Vol 22, Iss , Pp 337-346 (2016) |
op_relation |
http://www.sciencedirect.com/science/article/pii/S1756464616000049 https://doaj.org/toc/1756-4646 1756-4646 doi:10.1016/j.jff.2016.01.003 https://doaj.org/article/6065019848174b329066a76fc0423e03 |
op_doi |
https://doi.org/10.1016/j.jff.2016.01.003 |
container_title |
Journal of Functional Foods |
container_volume |
22 |
container_start_page |
337 |
op_container_end_page |
346 |
_version_ |
1766362904782700544 |