Anti-Candida and anti-quorum sensing activity of airborne microorganisms detected by a rapid method

Abstract INTRODUCTION: Introducing new antibiotics to the clinic is critical. METHODS: We adapted a plate method described by Kawaguchi and coworkers in 20131 for detecting inhibitory airborne microorganisms. RESULTS: We obtained 51 microbial colonies antagonist to Chromobacterium violaceum, purifie...

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Bibliographic Details
Published in:Revista da Sociedade Brasileira de Medicina Tropical
Main Authors: Andria Lopes Cruz, Fabiana Silva de Souza, Maxwel Adriano Abegg
Format: Article in Journal/Newspaper
Language:English
Published: Sociedade Brasileira de Medicina Tropical (SBMT) 2019
Subjects:
Candida sp
Chromobacterium violaceum
Quorum sensing
Antimicrobials
Arctic medicine. Tropical medicine
RC955-962
Arctic
Online Access:https://doi.org/10.1590/0037-8682-0152-2018
https://doaj.org/article/5844716f70d74c11bccf8adab2abd083
Description
Summary:Abstract INTRODUCTION: Introducing new antibiotics to the clinic is critical. METHODS: We adapted a plate method described by Kawaguchi and coworkers in 20131 for detecting inhibitory airborne microorganisms. RESULTS: We obtained 51 microbial colonies antagonist to Chromobacterium violaceum, purified and retested them, and of these, 39 (76.5%) were confirmed. They comprised 24 bacteria, 13 fungi, and 2 yeasts. Among the fungi, eight (61.5%) produced active extracts. Among the bacterial, yeast, and fungal strains, 17 (44.7%) and 12 (31.6%) were active against Candida albicans and Candida parapsilosis, respectively. CONCLUSIONS: The proposed screening method is a rapid strategy for discovering potential antibiotic producers.

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