Bilateral adrenal histoplasmosis in an immunocompetent man Histoplasmose adrenal bilateral em um homem imunocompetente

• Published in: Revista da Sociedade Brasileira de Medicina Tropical
• Main Authors: Carlos Frederico Lopes Benevides, Ronilson Oliveira Durães, Bianca Aquino, Leonardo de Lucca Schiavon, Janaína Luz Narciso-Schiavon, Fernando da Costa Buzzoleti
• Format: Article in Journal/Newspaper
• Language: English
• Published: Sociedade Brasileira de Medicina Tropical (SBMT) 2007
• Subjects: Histoplasma capsulatum; Histoplasmose disseminada; Tumor adrenal; Insuficiência adrenal; Disseminated histoplasmosis; Adrenal tumor; Adrenal insufficiency; Arctic medicine. Tropical medicine; RC955-962; Arctic
• Online Access: https://doi.org/10.1590/S0037-86822007000200017; https://doaj.org/article/538881a51a93433993b6e52080ca482f

Histoplasmosis is a fungal disease that is endemic in Brazil. It may present as chronic pulmonary infection or in disseminated form. Disseminated histoplasmosis frequently affects the adrenal gland; however, unilateral involvement in immunosuppressed patients is the usual presentation. We report a case of an elderly immunocompetent male with history of weight loss, fever and bilateral adrenal mass who was successfully treated with itraconazole. Histoplasmose é uma doença fúngica endêmica no Brasil que pode se apresentar como infecção pulmonar crônica ou na forma disseminada. A histoplasmose disseminada freqüentemente acomete a glândula adrenal; entretanto, ocorre mais em pacientes imunossuprimidos e de forma unilateral. Relatamos um caso de um homem idoso imunocompetente com história de perda de peso, febre e massa adrenal bilateral que foi tratada com itraconazol, com sucesso.