Collagen-Based Bioactive Bromelain Hydrolysate from Salt-Cured Cod Skin

Considerable amounts of fish processing by-products are discarded each year. About 30% of this material may be skin and bone. Fish skin has more than 80% of its total protein content as collagen. Furthermore, in recent years, there has been a growing demand for collagen-based peptides due to their b...

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Bibliographic Details
Published in:Applied Sciences
Main Authors: Ezequiel R. Coscueta, María Emilia Brassesco, Manuela Pintado
Format: Article in Journal/Newspaper
Language:English
Published: MDPI AG 2021
Subjects:
Atlantic cod skin
enzymatic hydrolysis
collagen
fishery by-products
bioactive peptides
bromelain
Technology
T
Engineering (General). Civil engineering (General)
TA1-2040
Biology (General)
QH301-705.5
Physics
QC1-999
Chemistry
QD1-999
atlantic cod
Online Access:https://doi.org/10.3390/app11188538
https://doaj.org/article/4bb1bc869a964193824b36eae473f6fb
Description
Summary:Considerable amounts of fish processing by-products are discarded each year. About 30% of this material may be skin and bone. Fish skin has more than 80% of its total protein content as collagen. Furthermore, in recent years, there has been a growing demand for collagen-based peptides due to their beneficial health effects. So, the objective of the present study was to optimise the obtaining bioactive hydrolysates from salt-cured cod skin using the protease Bromelain at 0.5% ( w / w ) concentration. This study developed a sustainable process that consumes less time and energy and uses an alternative source as raw material. In addition, bromelain allows hydrolysates with important antioxidant (ORAC, 514 μmol Trolox Equivalent/g protein) and antihypertensive activities (inhibition of ACE, IC 50 of 166 μg protein/mL) as well as excellent biocompatibility with dermal and subcutaneous cells.

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