Summary: | Os AA. trataram 40 crianças portadoras de amebíase intestinal crônica, cujas idades variaram entre dois (três casos) a seis anos (cinco doentes), com Etofamida na apresentação de suspensão (cada 5 ml contém 100 mg da substância ativa), na dose de 100 mg cinco vezes ao dia e durante três dias consecutivos (dose total de 1,5 g). O controle de cura parasitológica foi realizado pelas técnicas de Faust e cols. e de Hoffman, Pons e Janer no 10., 15.° e 25.° dias após o tratamento, sendo também usada a hematoxilina férrica neste último controle. Obtiveram os AA. 90% de cura parasitológica (36 enfermos) e excelente tolerância ao medicamento. A new antiamebic agent, Ethophamide, was tried in the treatment of 40 children suffering chronic intestinal amebiasis, of both sexes, and aged from two (three patient) to six years old (five patients). The drug was given in oral suspension containing 2% of Ethophamide, and the dosage used was 500 mg daily for three days. Laboratorial controls were made before the treatment and repeated 10, 15, and 25 days after its completion, and consisting of Faust & cols., Hoffman, Pons and Janer mehods, and iron hematoxylin (on the 25th day). After the treatment 36 patients (or 90%) were cured, and the tolerance to medication was considered very good. In the light of the excellent results obtained, the Authors concludes that Ethophamide could be the drug of choice for the treatment of amebiasis.
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