Leptomonas seymouri and Crithidia fasciculata exoantigens can discriminate human cases of visceral leishmaniasis from American tegumentary leishmaniasis ones

• Published in: Revista do Instituto de Medicina Tropical de São Paulo
• Main Authors: Norival Kesper, Marta Maria G. Teixeira, José Angelo L. Lindoso, Clara Lúcia Barbieri, Eufrosina Setsu Umezawa
• Format: Article in Journal/Newspaper
• Language: English
• Published: Universidade de São Paulo (USP)
• Subjects: Leptomonas seymouri; Crithidia fasciculata; Leishmania (Leishmania) infantum chagasi; Exoantigens; Leishmaniasis; Arctic medicine. Tropical medicine; RC955-962; Infectious and parasitic diseases; RC109-216; Arctic
• Online Access: https://doi.org/10.1590/s1678-9946201759001; https://doaj.org/article/4b18671655744c0b92416ead154cae07

ABSTRACT Exoantigens (exo) from Leptomonas seymouri and Crithidia fasciculata were used in an enzyme linked immunosorbent assay (ELISA), showing 100% reactivity with sera from visceral leishmaniasis (VL) cases, and no reactivity with American tegumentary leishmaniasis (ATL) ones. Our results have indicated that these exoantigens can be applied in the discrimination of VL and ATL cases.