Leptomonas seymouri and Crithidia fasciculata exoantigens can discriminate human cases of visceral leishmaniasis from American tegumentary leishmaniasis ones

ABSTRACT Exoantigens (exo) from Leptomonas seymouri and Crithidia fasciculata were used in an enzyme linked immunosorbent assay (ELISA), showing 100% reactivity with sera from visceral leishmaniasis (VL) cases, and no reactivity with American tegumentary leishmaniasis (ATL) ones. Our results have in...

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Bibliographic Details
Published in:Revista do Instituto de Medicina Tropical de São Paulo
Main Authors: Norival Kesper, Marta Maria G. Teixeira, José Angelo L. Lindoso, Clara Lúcia Barbieri, Eufrosina Setsu Umezawa
Format: Article in Journal/Newspaper
Language:English
Published: Universidade de São Paulo (USP)
Subjects:
Leptomonas seymouri
Crithidia fasciculata
Leishmania (Leishmania) infantum chagasi
Exoantigens
Leishmaniasis
Arctic medicine. Tropical medicine
RC955-962
Infectious and parasitic diseases
RC109-216
Arctic
Online Access:https://doi.org/10.1590/s1678-9946201759001
https://doaj.org/article/4b18671655744c0b92416ead154cae07
Description
Summary:ABSTRACT Exoantigens (exo) from Leptomonas seymouri and Crithidia fasciculata were used in an enzyme linked immunosorbent assay (ELISA), showing 100% reactivity with sera from visceral leishmaniasis (VL) cases, and no reactivity with American tegumentary leishmaniasis (ATL) ones. Our results have indicated that these exoantigens can be applied in the discrimination of VL and ATL cases.

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