Acute petrified myocardium associated with meningococcal sepsis in childhood-onset systemic lupus erythematous: a fatal case

ABSTRACT Acute petrified myocardium associated with septic shock, diagnosed by autopsy has rarely been described. A 15-year-old adolescent male was diagnosed with childhood-onset systemic lupus erythematosus. One year later, he was hospitalized with fever, myalgia, headache, arthritis, vomiting, dys...

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Bibliographic Details
Published in:Revista do Instituto de Medicina Tropical de São Paulo
Main Authors: Ana Carolina Etrusco Zaroni Santos, Michele Luglio, Artur Figueiredo Delgado, Constance Dell Santo Vieira Schuwartz, Heloísa Helena Sousa Marques, Clarissa Carvalho de Miranda Valões, Maria Andreina Cabrera Dominguez, Werther Brunow de Carvalho, Clovis Artur Silva, Amaro Nunes Duarte-Neto
Format: Article in Journal/Newspaper
Language:English
Published: Universidade de São Paulo (USP)
Subjects:
Myocardial calcification
Sepsis
Neisseria meningitides
Lupus
Intensive care
Arctic medicine. Tropical medicine
RC955-962
Infectious and parasitic diseases
RC109-216
Arctic
Online Access:https://doi.org/10.1590/s1678-9946201961039
https://doaj.org/article/47545b71e89f4193a864c28eddd972a6
Description
Summary:ABSTRACT Acute petrified myocardium associated with septic shock, diagnosed by autopsy has rarely been described. A 15-year-old adolescent male was diagnosed with childhood-onset systemic lupus erythematosus. One year later, he was hospitalized with fever, myalgia, headache, arthritis, vomiting, dyspnea and was diagnosed with sepsis secondary to bronchopneumonia and meningitis. Blood culture identified Neisseria meningitidis serogroup Y. Despite antibiotics and intensive therapeutic measures, he died after 29 days of hospitalization. The autopsy revealed necrotic cardiomyocytes with dystrophic calcification and interstitial fibrosis.

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