Childhood TB Surveillance: Bridging the Knowledge Gap to Inform Policy

Tuberculosis (TB) is a leading cause of death globally. Natural history studies show that young children are at particularly high risk of progression to active TB and severe, disseminated disease following infection. Despite this, high-quality regional and global surveillance data on the burden of c...

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Bibliographic Details
Published in:Journal of Tropical Medicine
Main Author: Andrew J. Brent
Format: Article in Journal/Newspaper
Language:English
Published: Hindawi Limited 2012
Subjects:
Online Access:https://doi.org/10.1155/2012/865436
https://doaj.org/article/43168d88f85344609f92b6eced4208de
Description
Summary:Tuberculosis (TB) is a leading cause of death globally. Natural history studies show that young children are at particularly high risk of progression to active TB and severe, disseminated disease following infection. Despite this, high-quality regional and global surveillance data on the burden of childhood TB are lacking. We discuss the unique aspects of TB in children that make diagnosis and therefore surveillance challenging; the limitations of available surveillance data; other data which provide insights into the true burden of childhood TB. Improved surveillance is among the key research priorities identified for childhood TB, but progress to date has been slow. Recent advances in TB diagnostics, and standardized clinical diagnostic guidelines and case definitions, all provide opportunities for new strategies to improve surveillance. Better-quality data on the burden and trends of childhood TB will inform and improve both public health policy and clinical practice.