Adverse drug events and the associated factors in patients with chronic Chagas disease
Abstract INTRODUCTION: Herein, we aimed to identify the factors associated with adverse drug events (ADEs) in chronic Chagas disease (CD) patients. METHODS: We analyzed 320 medical notes from 295 patients. The Naranjo algorithm was applied to determine the cause of ADEs. Mixed effects logistic regre...
Published in: | Revista da Sociedade Brasileira de Medicina Tropical |
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Online Access: | https://doi.org/10.1590/0037-8682-0443-2019 https://doaj.org/article/40e0a186c7844dee8256032d02c4f987 |
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ftdoajarticles:oai:doaj.org/article:40e0a186c7844dee8256032d02c4f987 2023-05-15T15:01:22+02:00 Adverse drug events and the associated factors in patients with chronic Chagas disease Luiza Braz da Cunha Lopes Raquel Rodrigues Pereira Patricia Mello Andrade Fernanda Martins Carneiro Mauro Felippe Felix Mediano Sophia Isabel Linnemann Kilgore Alejandro Marcel Hasslocher-Moreno Andréa Silvestre de Sousa Manoel Marques Evangelista Oliveira Roberto Magalhães Saraiva Marcelo Teixeira de Holanda Gilberto Marcelo Sperandio da Silva 2020-04-01T00:00:00Z https://doi.org/10.1590/0037-8682-0443-2019 https://doaj.org/article/40e0a186c7844dee8256032d02c4f987 EN eng Sociedade Brasileira de Medicina Tropical (SBMT) http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0037-86822020000100639&tlng=en https://doaj.org/toc/1678-9849 1678-9849 doi:10.1590/0037-8682-0443-2019 https://doaj.org/article/40e0a186c7844dee8256032d02c4f987 Revista da Sociedade Brasileira de Medicina Tropical, Vol 53 (2020) Chagas disease Adverse drug event Cardiomyopathy Arctic medicine. Tropical medicine RC955-962 article 2020 ftdoajarticles https://doi.org/10.1590/0037-8682-0443-2019 2022-12-31T03:20:23Z Abstract INTRODUCTION: Herein, we aimed to identify the factors associated with adverse drug events (ADEs) in chronic Chagas disease (CD) patients. METHODS: We analyzed 320 medical notes from 295 patients. The Naranjo algorithm was applied to determine the cause of ADEs. Mixed effects logistic regression was performed to evaluate the factors associated with ADEs. RESULTS: ADEs were described in 102 medical notes (31.9%). Captopril was most frequently associated with ADEs. Age (RR 0.96; 95%CI 0.94-0.99) and cardiac C/D stages (RR 3.24; 95%CI 1.30-4.58) were the most important clinical factors associated with ADEs. CONCLUSIONS: Close follow-up is warranted for CD patients. Article in Journal/Newspaper Arctic Directory of Open Access Journals: DOAJ Articles Arctic Revista da Sociedade Brasileira de Medicina Tropical 53 |
institution |
Open Polar |
collection |
Directory of Open Access Journals: DOAJ Articles |
op_collection_id |
ftdoajarticles |
language |
English |
topic |
Chagas disease Adverse drug event Cardiomyopathy Arctic medicine. Tropical medicine RC955-962 |
spellingShingle |
Chagas disease Adverse drug event Cardiomyopathy Arctic medicine. Tropical medicine RC955-962 Luiza Braz da Cunha Lopes Raquel Rodrigues Pereira Patricia Mello Andrade Fernanda Martins Carneiro Mauro Felippe Felix Mediano Sophia Isabel Linnemann Kilgore Alejandro Marcel Hasslocher-Moreno Andréa Silvestre de Sousa Manoel Marques Evangelista Oliveira Roberto Magalhães Saraiva Marcelo Teixeira de Holanda Gilberto Marcelo Sperandio da Silva Adverse drug events and the associated factors in patients with chronic Chagas disease |
topic_facet |
Chagas disease Adverse drug event Cardiomyopathy Arctic medicine. Tropical medicine RC955-962 |
description |
Abstract INTRODUCTION: Herein, we aimed to identify the factors associated with adverse drug events (ADEs) in chronic Chagas disease (CD) patients. METHODS: We analyzed 320 medical notes from 295 patients. The Naranjo algorithm was applied to determine the cause of ADEs. Mixed effects logistic regression was performed to evaluate the factors associated with ADEs. RESULTS: ADEs were described in 102 medical notes (31.9%). Captopril was most frequently associated with ADEs. Age (RR 0.96; 95%CI 0.94-0.99) and cardiac C/D stages (RR 3.24; 95%CI 1.30-4.58) were the most important clinical factors associated with ADEs. CONCLUSIONS: Close follow-up is warranted for CD patients. |
format |
Article in Journal/Newspaper |
author |
Luiza Braz da Cunha Lopes Raquel Rodrigues Pereira Patricia Mello Andrade Fernanda Martins Carneiro Mauro Felippe Felix Mediano Sophia Isabel Linnemann Kilgore Alejandro Marcel Hasslocher-Moreno Andréa Silvestre de Sousa Manoel Marques Evangelista Oliveira Roberto Magalhães Saraiva Marcelo Teixeira de Holanda Gilberto Marcelo Sperandio da Silva |
author_facet |
Luiza Braz da Cunha Lopes Raquel Rodrigues Pereira Patricia Mello Andrade Fernanda Martins Carneiro Mauro Felippe Felix Mediano Sophia Isabel Linnemann Kilgore Alejandro Marcel Hasslocher-Moreno Andréa Silvestre de Sousa Manoel Marques Evangelista Oliveira Roberto Magalhães Saraiva Marcelo Teixeira de Holanda Gilberto Marcelo Sperandio da Silva |
author_sort |
Luiza Braz da Cunha Lopes |
title |
Adverse drug events and the associated factors in patients with chronic Chagas disease |
title_short |
Adverse drug events and the associated factors in patients with chronic Chagas disease |
title_full |
Adverse drug events and the associated factors in patients with chronic Chagas disease |
title_fullStr |
Adverse drug events and the associated factors in patients with chronic Chagas disease |
title_full_unstemmed |
Adverse drug events and the associated factors in patients with chronic Chagas disease |
title_sort |
adverse drug events and the associated factors in patients with chronic chagas disease |
publisher |
Sociedade Brasileira de Medicina Tropical (SBMT) |
publishDate |
2020 |
url |
https://doi.org/10.1590/0037-8682-0443-2019 https://doaj.org/article/40e0a186c7844dee8256032d02c4f987 |
geographic |
Arctic |
geographic_facet |
Arctic |
genre |
Arctic |
genre_facet |
Arctic |
op_source |
Revista da Sociedade Brasileira de Medicina Tropical, Vol 53 (2020) |
op_relation |
http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0037-86822020000100639&tlng=en https://doaj.org/toc/1678-9849 1678-9849 doi:10.1590/0037-8682-0443-2019 https://doaj.org/article/40e0a186c7844dee8256032d02c4f987 |
op_doi |
https://doi.org/10.1590/0037-8682-0443-2019 |
container_title |
Revista da Sociedade Brasileira de Medicina Tropical |
container_volume |
53 |
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1766333396836941824 |