Pulmonary tuberculosis: hematology, serum biochemistry and the relation with the disease duration

• Published in: Journal of Venomous Animals and Toxins including Tropical Diseases
• Main Authors: V. M. Oliva, G. A. G. Cezário, R. A. Cocato, J. Marcondes-Machado
• Format: Article in Journal/Newspaper
• Language: English
• Published: SciELO 2008
• Subjects: Mycobacterium tuberculosis; pulmonary tuberculosis; smoking; hematolological and biochemical parameters; erythrocyte sedimentation rate; Arctic medicine. Tropical medicine; RC955-962; Toxicology. Poisons; RA1190-1270; Zoology; QL1-991; Arctic
• Online Access: https://doi.org/10.1590/S1678-91992008000100006; https://doaj.org/article/3d8c6fd0ee1146f7988d9aea7fe1054a

The aim of the present study was to analyze the relationship between hematological and biochemical parameters and tuberculosis process activity time according to clinical complaint duration. It was a retrospective study analyzing medical records from 80 pulmonary tuberculosis patients at Botucatu Medical School University Hospital (Botucatu, São Paulo State, Brazil), who were divided into 2 groups according to clinical complaint duration: Group 1 (G1) - up to three months; Group 2 (G2) - over three months. Parameters included: age, gender, bacilloscopy, erythrocyte sedimentation rate (ESR), platelet count, alpha1-globulin, alpha2-globulin, gamma globulin, mucoprotein, alpha1-acid glycoprotein values, and the presence of risk factors such as smoking, alcoholism, drug addiction, sexual promiscuity, contact with tuberculosis carriers, and previous treatment. Groups were compared by calculating t and p, and Chi-square (X²) and p. Comparisons revealed a tendency towards smoking with a higher frequency of smokers in G1 (0.05 0.05). A correlation was found between ESR, platelet count, smoking and less than three months clinical duration.