Pulmonary tuberculosis: hematology, serum biochemistry and the relation with the disease duration

The aim of the present study was to analyze the relationship between hematological and biochemical parameters and tuberculosis process activity time according to clinical complaint duration. It was a retrospective study analyzing medical records from 80 pulmonary tuberculosis patients at Botucatu Me...

Full description

Bibliographic Details
Published in:Journal of Venomous Animals and Toxins including Tropical Diseases
Main Authors: V. M. Oliva, G. A. G. Cezário, R. A. Cocato, J. Marcondes-Machado
Format: Article in Journal/Newspaper
Language:English
Published: SciELO 2008
Subjects:
Online Access:https://doi.org/10.1590/S1678-91992008000100006
https://doaj.org/article/3d8c6fd0ee1146f7988d9aea7fe1054a
Description
Summary:The aim of the present study was to analyze the relationship between hematological and biochemical parameters and tuberculosis process activity time according to clinical complaint duration. It was a retrospective study analyzing medical records from 80 pulmonary tuberculosis patients at Botucatu Medical School University Hospital (Botucatu, São Paulo State, Brazil), who were divided into 2 groups according to clinical complaint duration: Group 1 (G1) - up to three months; Group 2 (G2) - over three months. Parameters included: age, gender, bacilloscopy, erythrocyte sedimentation rate (ESR), platelet count, alpha1-globulin, alpha2-globulin, gamma globulin, mucoprotein, alpha1-acid glycoprotein values, and the presence of risk factors such as smoking, alcoholism, drug addiction, sexual promiscuity, contact with tuberculosis carriers, and previous treatment. Groups were compared by calculating t and p, and Chi-square (X²) and p. Comparisons revealed a tendency towards smoking with a higher frequency of smokers in G1 (0.05 0.05). A correlation was found between ESR, platelet count, smoking and less than three months clinical duration.