Buruli Ulcer: Treatment Challenges at Three Centres in Ghana

Aims. This retrospective study was to identify some challenges in the treatment of Buruli ulcer (BU) and present a proposed treatment regime. Materials and Methods. Information from patients medical records, hospital database, and follow-up findings on BU treatment procedures from 1994 to 1998 and f...

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Bibliographic Details
Published in:Journal of Tropical Medicine
Main Authors: Pius Agbenorku, Isaac K. Donwi, Pawson Kuadzi, Paul Saunderson
Format: Article in Journal/Newspaper
Language:English
Published: Wiley 2012
Subjects:
Online Access:https://doi.org/10.1155/2012/371915
https://doaj.org/article/3c0c02824c2d4ff088261e6072d49fa8
Description
Summary:Aims. This retrospective study was to identify some challenges in the treatment of Buruli ulcer (BU) and present a proposed treatment regime. Materials and Methods. Information from patients medical records, hospital database, and follow-up findings on BU treatment procedures from 1994 to 1998 and from 2004 to 2007 at three research sites in Ghana were reviewed to determine the treatment challenges encountered. Data needed were recorded and analyzed, and results presented using SPSS version 17.0. Results. A total of 489 BU patients information was selected for the study. A majority (56.90%, ) of the patients were children (0–14 years), with a mean age of 12.8 years. Significant challenges in BU treatment in Ghana identified included sequelae ( ), delayed treatment ( ), and high treatment cost ( ). Duration of hospital stay was clearly correlated with the time spent at home prior to admission; spearman’s rank correlation coefficient was 0.72 (95% CI 0.42–0.87). Conclusion. Delays in seeking treatment among BU patients were the main factor which resulted in most of the other factors contributing to the challenges in treatment. A combination of psychosocial and biomedical approach was proposed as holistic method to alleviate the challenges in BU treatment.